icpeptide@gmail.comThis website has been online since June 2016.

MBP (85–99) - EKPKVEAYKAAAAPA – Multiple sclerosis peptides

MBP (Myelin basic protein - UniProtKB - P04370) is a protein of around 18 ,5 kDA. MBP is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. Myelin basic protein is believed to be important in the process of myelination of nerves in the nervous system. Antibodies against Myelin Basic Protein have shown a role in the pathogenesis of MS (Multiple Sclerosis) like in experimental autoimmune encephalomyelitis. MBP (85-99) peptide is a fragment of MBP protein used in research to induce EAE (experimental autoimmune encephalomyelitis) due to the binding with the leukocyte human (HLA)-DR2. MBP (myelin basic protein) 85-99 is used to stimulate immune response and CD4+ T cell activity.

Technical specification

SequenceEKPKVEAYKAAAAPA
MW1543.76 g / mol (C₇₀H₁₁₄N₁₈O₂₁)
Purity> 95%
Counter-ionTFA Salts (see option TFA removal)
Delivery formatFreeze dried in polypropylene 2mL microtubes

Price

ProductSizePrice €Price $
NJ137-1MG1 mg110 €138 $
NJ137-5MG5 mg385 €481 $